Episode 3 - Affecting fat loss in rodents by caloric restriction, knocking out insulin genes and seeing how incretin hormones play into it
In Episode 3 of the Break Nutrition show we discussed rodent studies showing an insulin gene dosage-dependent effect on adiposity, the interplay between caloric restriction & circulating insulin, as well as how incretin hormones affect fat loss dynamics.
Caloric Restriction Paradoxically Increases Adiposity in Mice With Genetically Reduced Insulin.
Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity.
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