Episode 3 - Affecting fat loss in rodents by caloric restriction, knocking out insulin genes and seeing how incretin hormones play into it
In Episode 3 of the Break Nutrition show we discussed rodent studies showing an insulin gene dosage-dependent effect on adiposity, the interplay between caloric restriction & circulating insulin, as well as how incretin hormones affect fat loss dynamics.
Caloric Restriction Paradoxically Increases Adiposity in Mice With Genetically Reduced Insulin.
Link: https://www.ncbi.nlm.nih.gov/m/pubmed/27145011/
Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity.
Link: https://www.ncbi.nlm.nih.gov/m/pubmed/26155745/?i=3&from=/27145011/related