Episode 6 – why bariatric surgery improves metabolic parameters quickly

Episode 5 of the Break Nutrition Show Gabor and I  had a discussion about the paper called “Mechanisms facilitating weight loss and resolution of type 2 diabetes following bariatric surgery”. Mechanisms facilitating weight loss and resolution of type 2 diabetes following bariatric surgery Link: https://www.ncbi.nlm.nih.gov/pubmed/20133150 Bariatric surgery is more akin to metabolic surgery than a procedure to mechanically restricting food intake The 3 classical categories of bariatric surgery (1) restrictive (2) malabsorptive (3) hybrid of 1 & 2 Improvement of metabolic

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Episode 3 – Affecting fat loss in rodents by caloric restriction, knocking out insulin genes and seeing how incretin hormones play into it

In Episode 3 of the Break Nutrition show we discussed rodent studies showing an insulin gene dosage-dependent effect on adiposity, the interplay between caloric restriction & circulating insulin, as well as how incretin hormones affect fat loss dynamics. Caloric Restriction Paradoxically Increases Adiposity in Mice With Genetically Reduced Insulin. Link: https://www.ncbi.nlm.nih.gov/m/pubmed/27145011/ Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity. Link: https://www.ncbi.nlm.nih.gov/m/pubmed/26155745/?i=3&from=/27145011/related

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