Blog Posts

Episode 29 – Steven Hamley zooms in & out on dietary patterns affecting our health

Show notes: Steven Hamley’s website http://www.stevenhamley.com.au/ and Twitter @stevenhamley I ask Steven why he started his blog and he explains that it all started when coming across the Paleo concept in 2010, sparking his interest in health and disease given the utility of this framework compared to traditional modes of viewing these matters. We talk about the following points mentioned in the AHA’s 2017 Presidential Advisory paper “In summary, randomized controlled trials that lowered intake of dietary saturated fat and

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Cannabis la pharmacopeia (Part 1)

Cannabis, something for everyone There are some things in this world which, when you learn about them, you learn about much more than you bargained for. Some ‘things’ connect to so many subjects from different magisteria that anyone can find something that interests them. Cannabis might be the prime example of that. It was for me, serendipitously turning me (back?) into a scientist at the ripe old age of 20. Plainly stated, there is no aspect of this plant that

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Can you improve your body composition by eating keto and doing resistance training?

Ketosis the metabolic state We go in and out of ketosis. You’re said to be in ketosis, vaguely, when you have ≥ 0.5 mmol/L of beta-hydroxybutyrate (BhB) in your blood. If you eat a lot more food than you need (hypercaloric) or just what you need to maintain your physique (eucaloric), you can do so in and out of ketosis. After 2 days of fasting most people will be in ketosis. Newborns reared on breast-milk are also ketogenic [1]. By exercising

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Episode 28 – Amber O’Hearn says meat heals & birds fly

  Show notes: Amber’s guest post Ketogenic diet and Vitamin C: the 101 Amber’s website http://www.ketotic.org/ Amber’s Ketofest 2017 video presentation In her presentation Amber explains that that animal sourced foods (AFS) score high in terms of diet quality, defined as the addition of 3 differently weighted parameters in the following formula ⇒ structural plant parts (e.g. indigestible cellulose) [weighting x2] Plant reproductive parts (e.g. starchy bulbs) [weighting x3.5] Animal prey (e.g. red meat) “[…] If our teeth aren’t well

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Episode 27 – Adipocytes and insulin resistance

Show notes:   60% of US adults are overweight to moderately obese but within that group there is great heterogeneity in their response to insulin ⇒ their degree of insulin sensitivity can vary more than sixfold at any given BMI within this range Adults constantly form and replace adipose cells, called turnover 2 places to measure fat are the femoral (leg fat) and subcutaneous (under your skin and predominantly white) adipose tissues For IMGU (insulin mediated glucose uptake), the higher

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Episode 26 – Dr.Bikman: well behaved fat and good insulin signaling FTW

Discuss further on: https://ask.breaknutrition.com Show notes: Here’s Dr.Bikman’s Twitter profile The Bikman lab is in The College of Life Sciences of Brigham Young University It focuses on identifying first “the molecular mechanisms that explain the increased risk of disease that accompanies weight gain, with particular emphasis on the etiology of insulin resistance and disrupted mitochondrial function. Second, we hope to reveal novel cellular processes that are responsible for fat development” Dr.Bikman enumerates some of the metabolic drugs used in disease

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Episode 25 – Larry & Kay Lynne Diamond: education is power

Show notes: Larry started LCHF May 2013 lost 45kg (100lbs) Larry’s fat-loss and health journey on www.dietdoctor.com He’s @natureboyrr on Twitter Kay Lynne started LCHF lost 32kg (70lbs) Kay Lynne’s fat-loss and health journey on www.marksdailyapple.com I ask Larry and Kay Lynne about how to best teach kids about food and health Kay Lynne explains the social challenge inherent for her daughter given she eats healthily (meat, vegetables, tubers and fruit) instead of the junk-food her classmates eat, but that

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Episode 24 – Tucker and Gabor on Seed Oils vs Refined Carbs – Part 2

Show notes: You can find Tucker Goodrich at http://yelling-stop.blogspot.com and on Twitter @tuckergoodrich Oxidative stress is the inevitable result of metabolism and basic chemistry, resulting from reactive oxygen species (ROS) like “slow” reacting hydrogen peroxide and “fast” reacting peroxyl radicals. Omega-6 and omega-3 PUFAs form peroxidation products like malondialdehyde, 4-hydroxynonenal (HNE) , isoprostanes or 9- and 13-hydroxyoctadecadienoic acids. Here’s a study from 2015 for more on PUFA chemistry.  PUFAs are not stable at the physiological temperature of ~37°C. When anti-oxidant action is lacking

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Why controlling gluconeogenesis is important for reversing diabetes?

Introduction: our very own sugar factory Step into the low-carb world and soon enough you’ll hear the term GlucoNeoGenesis. GNG for short, is your body’s ability to construct glucose, a kind of sugar, out of molecules that aren’t glucose. It does this to ensure that, if you don’t eat any carbs, the cells in your body that need glucose will still get enough of it. It’s one reason why humans are so good at fasting or delaying death from starvation

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Episode 23 – Tucker Goodrich dishes on bad fats

Show notes: Tucker’s blog is http://yelling-stop.blogspot.com and his Twitter is @tuckergoodrich Could avoiding seed oils be why Tucker, I and others have noticed the same anecdotal experience of increased resistance to sunburn? We discuss the apportioning of seed oils, refined flours and sugars to diseases of civilization (2004) Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA “In summary, chronic caloric excess of n-6 PUFA when coupled with acute diabetes of only 4 days precipitated mitochondrial

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