Blog Posts

Cold thermogenesis: how to freeze your fat off

Cold_thermogenesis_how_to_freeze_your_fat_off

Technology as a crutch The industrial age started in the late 18th century in the United Kingdom and with it, brought about technologies that now keep us in the Goldilocks zone, not too hot not too cold. In effect, we outsourced a fundamental aspect of what it means to stay alive and well temperature control Specifically, we now do very little cold thermogenesis. It’s a process mammals like us use to produce heat in order to stay warm. Our bodies

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Episode 14 – Freezing your fat off

Show notes: Study è “Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus” (Hanssen et al. 2015) Brown adipose tissue (BAT) was ‘rediscovered’ in 2009 Cold exposure increases BAT & its activity BAT activity was determined by measured glucose uptake via 18FDG PET-CT Data suggests BAT activation correlates with decreased triglycerides in BAT tissue More glucose was taken up (on average) in skeletal muscle & BAT tissue post-cold adaptation Uncoupling potein-1 (UCP-1) expressing white adipose tissue

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Is a Vegan Ketogenic diet Possible ?

is a vegan ketogenic diet possible

Your friend the vegan Picture this. Your friend the vegan who’s always up on the latest plant-based superfood suddenly mentions wanting to try this thing called a ketogenic diet – more specifically, a vegan ketogenic diet. You’re told a ketogenic diet is super high in fat and very low in carbs. Because you’re a good friend, you think about what they’re saying, only to realize that vegan diets aren’t particularly fatty. Plants tend to store a lot of starch or

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Episode 13 – What happens to fructose-fed monkeys?

Short summary: In episode 13 Gabor and I review a 2011 study looking at the metabolic consequences of rhesus monkeys being fed a grain-based diet supplemented with 500mL of fructose loaded Kool-Aid a day over a year. Show notes: The study: Fructose-Fed Rhesus Monkeys: A Nonhuman Primate Model of Insulin Resistance, Metabolic Syndrome, and Type 2 Diabetes (Bremer et al. 2001) Gabor explains what is fructose, glucose and high-fructose corn syrup (HFCS) Gabor explains the enzymatic means by which HFCS

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Treatment for Metabolic Syndrome

treatment for metabolic syndrome

What is the metabolic syndrome? Metabolic syndrome is a set of criteria used to identify a pathological state of metabolism. If you qualify as having metabolic syndrome, this means one or more aspects of your metabolism is out of whack such that your odds of suffering from heart disease, stroke, diabetes, obesity, cancer etc. are substantially increased. Metabolic syndrome is identified by measuring five markers: waist circumference (WC), HDL cholesterol (HDLc), triglycerides (TG),  fasting plasma glucose (FPG) and both systolic

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Episode 12 – Decoding Cholesterol with Dave Feldman

Short summary: I talk to engineer Dave Feldman about what his dietary self-experiments taught him cholesterol in human physiology. His “N = 1” experimentation is not only very interesting and rigorous but most importantly, it cannot be explained by current mainstream notions in lipidology. We also discuss the implications that this may have for cardiovascular disease. Show notes: Dave Feldman is known as the Christian Bale of nutrition for his extreme self-experiments where he ate 5,000 kcals per day, or

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Episode 11 – Obesity: a bird’s eye view

Short summary: In episode 11 Gabor selects 2 papers on the physiology of migrating birds that fatten up for their voyage and we discuss what this can tell us about human obesity. The first paper is from 2002 by Bairlein and is called “How to get fat: nutritional mechanisms of seasonal fat accumulation in migratory songbirds” http://www.ncbi.nlm.nih.gov/pubmed/12008967. The second is called “Adipose energy stores, physical work, and the metabolic syndrome: lessons from hummingbirds” http://www.ncbi.nlm.nih.gov/pubmed/16351726 and is by Hargrove et al.

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What is the keto flu or low carb flu and what to do about it?

keto-flu

Keto flu symptoms, mitigation and getting over excess carbohydrates Any major dietary or lifestyle change has the potential to cause discomfort or lets face it, even mess you up for a bit. This is sometimes referred to as a ‘flu’. It’s the most common time during which people will quit their dietary or lifestyle shift as many simply feel they are unable to function without significant carbohydrates and snacking throughout day. Here we’ll discuss the major downside to starting a

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Episode 10 – Medical uses of ketogenic and low carb diets with Ellen Davis

Short summary: With guest Ellen Davis we discuss the many medical applications of ketogenic and low carb diets, all of which is explored in depth in her 3 books “Fighting Cancer with a Ketogenic Diet”, “The Ketogenic Diet for Type 1 Diabetes” and “Conquering Type 2 Diabetes with a Ketogenic Diet”. Show notes: • Ellen’s books “Fighting Cancer with a Ketogenic Diet”, “The Ketogenic Diet for Type 1 Diabetes” and “Conquering Type 2 Diabetes with a Ketogenic Diet” • Who

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Kickstart your basic keto diet

kickstart-your-basic-keto-diet

What’s a basic keto diet? A basic keto diet is considerably higher in fat and lower in carbs than is typical of modern diets with pasta, bread and potatoes as their staples. Your protein intake will remain pretty much the same, although if in doubt, it may be wise to eat a little more considering many older Americans don’t get enough [x]. Plainly stated, this means most of your calories will come from fat, about a quarter from protein and

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